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Ann Transl Med 7(18):440 Xu X et al (2020) Pyrroloquinoline quinone can prevent chronic heart failure by regulating mitochondrial function

Andrew Huberman: So when vitamin D gets into cells and it's binding to these VDREs, what sorts of things are they triggering

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Hydrogen bonds, however, are distinct from dipoledipole interactions for two main reasons: (1) fluorine, oxygen, and nitrogen are highly electronegative, so the partial charges involved are large, and (2) the hydrogen atom is very small, which allows the partial positive charge on hydrogen to be very close to the partial negative charge on the H-bond acceptor